Cancer Metastasis
What is Cancer Metastasis?
Metastasis, the spread of cancer cells from the primary tumor to distant sites in the body, is the leading cause of cancer-related deaths. Developing treatments to prevent or inhibit metastasis is a critical goal in improving patient outcomes.
The metastatic process involves multiple steps, including local invasion, intravasation into blood or lymphatic vessels, survival during transit, extravasation into new tissue, and colonization at distant sites. Cancer cells undergo phenotypic changes and interact with the tumor microenvironment to facilitate each step.
NFCR IMPACTS IN CANCER METASTASIS RESEARCH
- NFCR recognizes pioneering scientists that established paradigms in metastasis research and clinical approaches.
NFCR-Supported Researchers Working on Cancer Metastasis
Paul Schimmel, Ph.D.
Scripps Research
Xiang-Lei Yang, Ph.D.
Scripps Research
Daniel A. Haber, M.D., Ph.D.
Massachusetts General Hospital Cancer Center
Esther Rheinbay, Ph.D.
Massachusetts General Hospital Cancer Center, Harvard Medical School
Danny R. Welch, Ph.D.
University of Kansas Cancer Center
Isidore Rigoutsos, Ph.D.
University Sidney Kimmel Cancer Center
Kornelia Polyak, M.D., Ph.D
Dana-Farber Cancer Institute and Harvard Medical School
Valerie M. Weaver, Ph.D
University of California San Francisco
Ronald A. DePinho, M.D.
University of Texas MD Anderson Cancer Center
Paul Fisher, M.Ph., Ph.D.
Virginia Commonwealth University
Francesca Bersani, Ph.D.
University of Torino, Italy
Aditya Bardia, M.D.
Massachusetts General Hospital & Harvard Medical School
Darren Carpizo, M.D., Ph.D.
University of Rochester
Igor Astsaturov, M.D., Ph.D.
Fox Chase Cancer Center
Webster K. Cavenee, Ph.D.
Ludwig Institute for Cancer Research
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